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SMILES: Cc1cc(NC(=O)Nc2ccc(cc2)-c2ncccn2)c2ccccc2n1

InChI Key: InChIKey=CIFJYAMSSPGZFE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326799   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))		BDBM50326799
PNG
(1-(2-methylquinolin-4-yl)-3-(4-(pyrimidin-2-yl)phe...)
Show SMILES Cc1cc(NC(=O)Nc2ccc(cc2)-c2ncccn2)c2ccccc2n1
Show InChI InChI=1S/C21H17N5O/c1-14-13-19(17-5-2-3-6-18(17)24-14)26-21(27)25-16-9-7-15(8-10-16)20-22-11-4-12-23-20/h2-13H,1H3,(H2,24,25,26,27)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



San Francisco State University

Curated by ChEMBL


Assay Description
Inhibition of recombinant IGF1R by ELISA

Bioorg Med Chem 18: 5995-6005 (2010)


Article DOI: 10.1016/j.bmc.2010.06.071
BindingDB Entry DOI: 10.7270/Q27944WQ
More data for this
Ligand-Target Pair