BDBM50327001 CHEMBL1254087::N-Ethyl-5-methyl-4-(2-methyl-5-(methylcarbamoyl)phenylamino)-pyrrolo[1,2-f][1,2,4]triazine-6-carboxamide

SMILES: CCNC(=O)c1cn2ncnc(Nc3cc(ccc3C)C(=O)NC)c2c1C

InChI Key: InChIKey=UGTNWXCECVALNT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327001 (CHEMBL1254087 | N-Ethyl-5-methyl-4-(2-methyl-5-(me...) Show SMILES CCNC(=O)c1cn2ncnc(Nc3cc(ccc3C)C(=O)NC)c2c1C Show InChI InChI=1S/C19H22N6O2/c1-5-21-19(27)14-9-25-16(12(14)3)17(22-10-23-25)24-15-8-13(18(26)20-4)7-6-11(15)2/h6-10H,5H2,1-4H3,(H,20,26)(H,21,27)(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	397	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of bacterially expressed p38alpha pretreated for 10 mins measured after 45 mins				J Med Chem 53: 6629-39 (2010) Article DOI: 10.1021/jm100540x BindingDB Entry DOI: 10.7270/Q2JM29T1
					More data for this Ligand-Target Pair