BindingDB logo
myBDB logout

BDBM50327706 2-(1-(2-methylbuta-1,3-dienyl)-5-m-tolyl-1H-indol-3-yl)acetamide::CHEMBL1258095

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-n1cc(-[#6]-[#6](-[#7])=O)c2cc(ccc12)-c1cccc(-[#6])c1

InChI Key: InChIKey=KWRLMHWUPSNNAP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327706   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Isoprenylcysteine carboxyl methyltransferase


(Homo sapiens (Human))		BDBM50327706
PNG
(2-(1-(2-methylbuta-1,3-dienyl)-5-m-tolyl-1H-indol-...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-n1cc(-[#6]-[#6](-[#7])=O)c2cc(ccc12)-c1cccc(-[#6])c1
Show InChI InChI=1S/C22H24N2O/c1-15(2)9-10-24-14-19(13-22(23)25)20-12-18(7-8-21(20)24)17-6-4-5-16(3)11-17/h4-9,11-12,14H,10,13H2,1-3H3,(H2,23,25)
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.70E+3n/an/an/an/an/an/a



National University of Singapore

Curated by ChEMBL


Assay Description
Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting

J Med Chem 53: 6838-50 (2010)


Article DOI: 10.1021/jm1002843
BindingDB Entry DOI: 10.7270/Q2VT1SB1
More data for this
Ligand-Target Pair