BDBM50327727 CHEMBL1257398::ethyl 2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetate
SMILES: CCCCCCCCn1cc(CC(=O)OCC)c2cc(ccc12)-c1cccc(C)c1
InChI Key: InChIKey=WUJQRINCIKGQRT-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human)) | BDBM50327727![]() (CHEMBL1257398 | ethyl 2-(1-octyl-5-m-tolyl-1H-indo...) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National University of Singapore Curated by ChEMBL | Assay Description Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting | J Med Chem 53: 6838-50 (2010) Article DOI: 10.1021/jm1002843 BindingDB Entry DOI: 10.7270/Q2VT1SB1 | |||||||||||
More data for this Ligand-Target Pair |