BDBM50327731 CHEMBL1257625::N-ethyl-N-((1-octyl-5-p-tolyl-1H-indol-3-yl)methyl)ethanamine

SMILES: CCCCCCCCn1cc(CN(CC)CC)c2cc(ccc12)-c1ccc(C)cc1

InChI Key: InChIKey=KGOKUWMVDMLYIS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human))	BDBM50327731 (CHEMBL1257625 | N-ethyl-N-((1-octyl-5-p-tolyl-1H-i...) Show SMILES CCCCCCCCn1cc(CN(CC)CC)c2cc(ccc12)-c1ccc(C)cc1 Show InChI InChI=1S/C28H40N2/c1-5-8-9-10-11-12-19-30-22-26(21-29(6-2)7-3)27-20-25(17-18-28(27)30)24-15-13-23(4)14-16-24/h13-18,20,22H,5-12,19,21H2,1-4H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting				J Med Chem 53: 6838-50 (2010) Article DOI: 10.1021/jm1002843 BindingDB Entry DOI: 10.7270/Q2VT1SB1
					More data for this Ligand-Target Pair