BDBM50327737 2-(5-fluoro-1-(3-methylbut-2-enyl)-1H-indol-3-yl)acetamide::CHEMBL1255997

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-n1cc(-[#6]-[#6](-[#7])=O)c2cc(F)ccc12

InChI Key: InChIKey=VQXFFCQRQHZMOL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human))	BDBM50327737 (2-(5-fluoro-1-(3-methylbut-2-enyl)-1H-indol-3-yl)a...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-n1cc(-[#6]-[#6](-[#7])=O)c2cc(F)ccc12 Show InChI InChI=1S/C15H17FN2O/c1-10(2)5-6-18-9-11(7-15(17)19)13-8-12(16)3-4-14(13)18/h3-5,8-9H,6-7H2,1-2H3,(H2,17,19)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation counting				J Med Chem 53: 6838-50 (2010) Article DOI: 10.1021/jm1002843 BindingDB Entry DOI: 10.7270/Q2VT1SB1
					More data for this Ligand-Target Pair