BDBM50327812 1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)urea::CHEMBL1257516::US9296693, 8

SMILES: CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc2ccccc2c1

InChI Key: InChIKey=TZULJTFMCGRCBK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50327812 (1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)u...) Show SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C19H23N3O2/c1-2-18(23)22-11-9-16(10-12-22)20-19(24)21-17-8-7-14-5-3-4-6-15(14)13-17/h3-8,13,16H,2,9-12H2,1H3,(H2,20,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.0	n/a
The Regents of the University of California US Patent					Assay Description IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...				US Patent US9296693 (2016) BindingDB Entry DOI: 10.7270/Q2TX3D7M
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50327812 (1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)u...) Show SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C19H23N3O2/c1-2-18(23)22-11-9-16(10-12-22)20-19(24)21-17-8-7-14-5-3-4-6-15(14)13-17/h3-8,13,16H,2,9-12H2,1H3,(H2,20,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assay				J Med Chem 53: 7067-75 (2010) Article DOI: 10.1021/jm100691c BindingDB Entry DOI: 10.7270/Q2GH9J6V
					More data for this Ligand-Target Pair
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50327812 (1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)u...) Show SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C19H23N3O2/c1-2-18(23)22-11-9-16(10-12-22)20-19(24)21-17-8-7-14-5-3-4-6-15(14)13-17/h3-8,13,16H,2,9-12H2,1H3,(H2,20,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assay				J Med Chem 53: 7067-75 (2010) Article DOI: 10.1021/jm100691c BindingDB Entry DOI: 10.7270/Q2GH9J6V
					More data for this Ligand-Target Pair
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50327812 (1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)u...) Show SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C19H23N3O2/c1-2-18(23)22-11-9-16(10-12-22)20-19(24)21-17-8-7-14-5-3-4-6-15(14)13-17/h3-8,13,16H,2,9-12H2,1H3,(H2,20,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	7.0	n/a
The Regents of the University of California US Patent					Assay Description IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...				US Patent US9296693 (2016) BindingDB Entry DOI: 10.7270/Q2TX3D7M
					More data for this Ligand-Target Pair