null

SMILES: CN(C)c1cccc2c(cccc12)S(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=SDLXTGGQDFKXAN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327856   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epoxide hydrolase 1 (Homo sapiens (Human))	BDBM50327856 (1-(1-(5-(Dimethylamino)naphthalen-1-ylsulfonyl)pip...) Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C25H27F3N4O4S/c1-31(2)22-7-3-6-21-20(22)5-4-8-23(21)37(34,35)32-15-13-18(14-16-32)30-24(33)29-17-9-11-19(12-10-17)36-25(26,27)28/h3-12,18H,13-16H2,1-2H3,(H2,29,30,33)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Inhibition assay of human soluble epoxide hydrolases.				US Patent US8501783 (2013) BindingDB Entry DOI: 10.7270/Q2W66JD1
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50327856 (1-(1-(5-(Dimethylamino)naphthalen-1-ylsulfonyl)pip...) Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C25H27F3N4O4S/c1-31(2)22-7-3-6-21-20(22)5-4-8-23(21)37(34,35)32-15-13-18(14-16-32)30-24(33)29-17-9-11-19(12-10-17)36-25(26,27)28/h3-12,18H,13-16H2,1-2H3,(H2,29,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assay				J Med Chem 53: 7067-75 (2010) Article DOI: 10.1021/jm100691c BindingDB Entry DOI: 10.7270/Q2GH9J6V
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50327856 (1-(1-(5-(Dimethylamino)naphthalen-1-ylsulfonyl)pip...) Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C25H27F3N4O4S/c1-31(2)22-7-3-6-21-20(22)5-4-8-23(21)37(34,35)32-15-13-18(14-16-32)30-24(33)29-17-9-11-19(12-10-17)36-25(26,27)28/h3-12,18H,13-16H2,1-2H3,(H2,29,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.0	n/a
The Regents of the University of California US Patent					Assay Description IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...				US Patent US9296693 (2016) BindingDB Entry DOI: 10.7270/Q2TX3D7M
					More data for this Ligand-Target Pair