BDBM50328014 3-[(1-Methyl-2(S)-pyrrolidinyl)methoxy]-5-(piperidinyl)pyridine Hydrochloride::CHEMBL1258464

SMILES: CN1CCC[C@H]1COc1cncc(c1)N1CCCCC1

InChI Key: InChIKey=YNWSSCRJTNUEHS-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50328014 (3-[(1-Methyl-2(S)-pyrrolidinyl)methoxy]-5-(piperid...) Show SMILES CN1CCC[C@H]1COc1cncc(c1)N1CCCCC1 |r| Show InChI InChI=1S/C16H25N3O/c1-18-7-5-6-14(18)13-20-16-10-15(11-17-12-16)19-8-3-2-4-9-19/h10-12,14H,2-9,13H2,1H3/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inactivation of nAChR alpha4beta2 in human SH-EP1 cells				J Med Chem 53: 6973-85 (2010) Article DOI: 10.1021/jm100765u BindingDB Entry DOI: 10.7270/Q25B03RQ
					More data for this Ligand-Target Pair