BDBM50328737 (R)-3-amino-4-chloro-N-(2-(4-(4-fluoro-2-(methylsulfonyl)phenyl)piperazin-1-yl)-2-oxo-1-phenylethyl)benzamide::CHEMBL1270952

SMILES: CS(=O)(=O)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@H](NC(=O)c1ccc(Cl)c(N)c1)c1ccccc1

InChI Key: InChIKey=HOROKZNFTIWWGZ-XMMPIXPASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50328737 ((R)-3-amino-4-chloro-N-(2-(4-(4-fluoro-2-(methylsu...) Show SMILES CS(=O)(=O)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@H](NC(=O)c1ccc(Cl)c(N)c1)c1ccccc1 |r| Show InChI InChI=1S/C26H26ClFN4O4S/c1-37(35,36)23-16-19(28)8-10-22(23)31-11-13-32(14-12-31)26(34)24(17-5-3-2-4-6-17)30-25(33)18-7-9-20(27)21(29)15-18/h2-10,15-16,24H,11-14,29H2,1H3,(H,30,33)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of factor 10a				J Med Chem 53: 6243-74 (2010) Article DOI: 10.1021/jm100146h BindingDB Entry DOI: 10.7270/Q2CR5VBB
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