BDBM50329369 (R)-1-(4-chlorophenyl)-4-(dimethylamino)-1-phenylbutan-1-ol::CHEMBL1270617

SMILES: CN(C)CCCC(O)(c1ccccc1)c1ccc(Cl)cc1

InChI Key: InChIKey=BHDKRQLGMSJVTR-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50329369 ((R)-1-(4-chlorophenyl)-4-(dimethylamino)-1-phenylb...) Show SMILES CN(C)CCCC(O)(c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H22ClNO/c1-20(2)14-6-13-18(21,15-7-4-3-5-8-15)16-9-11-17(19)12-10-16/h3-5,7-12,21H,6,13-14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to Bcl-XL by NMR titration assay				Bioorg Med Chem Lett 20: 6587-91 (2010) Article DOI: 10.1016/j.bmcl.2010.09.033 BindingDB Entry DOI: 10.7270/Q2J103C3
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50329369 ((R)-1-(4-chlorophenyl)-4-(dimethylamino)-1-phenylb...) Show SMILES CN(C)CCCC(O)(c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H22ClNO/c1-20(2)14-6-13-18(21,15-7-4-3-5-8-15)16-9-11-17(19)12-10-16/h3-5,7-12,21H,6,13-14H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 by NMR titration assay				Bioorg Med Chem Lett 20: 6587-91 (2010) Article DOI: 10.1016/j.bmcl.2010.09.033 BindingDB Entry DOI: 10.7270/Q2J103C3
					More data for this Ligand-Target Pair