BDBM50329372 (S)-2-amino-1-(2-chloro-4-fluorophenyl)-1-phenylethanol::CHEMBL1269480
SMILES: NCC(O)(c1ccccc1)c1ccc(F)cc1Cl
InChI Key: InChIKey=HKJNZTZRKHIRFT-UHFFFAOYSA-N
Data: 1 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM50329372 ((S)-2-amino-1-(2-chloro-4-fluorophenyl)-1-phenylet...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.50E+5 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity to Bcl-2 by NMR titration assay | Bioorg Med Chem Lett 20: 6587-91 (2010) Article DOI: 10.1016/j.bmcl.2010.09.033 BindingDB Entry DOI: 10.7270/Q2J103C3 | |||||||||||
More data for this Ligand-Target Pair |