BDBM50329378 4'-(2-(3-(4-(dimethylamino)-1-hydroxy-1-phenylbutyl)phenoxy)ethyl)biphenyl-4-carboxylic acid::CHEMBL1270922

SMILES: CN(C)CCCC(O)(c1ccccc1)c1cccc(OCCc2ccc(cc2)-c2ccc(cc2)C(O)=O)c1

InChI Key: InChIKey=GXMWGSRSTMANHE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50329378 (4'-(2-(3-(4-(dimethylamino)-1-hydroxy-1-phenylbuty...) Show SMILES CN(C)CCCC(O)(c1ccccc1)c1cccc(OCCc2ccc(cc2)-c2ccc(cc2)C(O)=O)c1 Show InChI InChI=1S/C33H35NO4/c1-34(2)22-7-21-33(37,29-8-4-3-5-9-29)30-10-6-11-31(24-30)38-23-20-25-12-14-26(15-13-25)27-16-18-28(19-17-27)32(35)36/h3-6,8-19,24,37H,7,20-23H2,1-2H3,(H,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Bcl-2 by fluorescence polarization assay				Bioorg Med Chem Lett 20: 6587-91 (2010) Article DOI: 10.1016/j.bmcl.2010.09.033 BindingDB Entry DOI: 10.7270/Q2J103C3
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