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BDBM50329385 4'-(2-(4-(4-(dimethylamino)-1-hydroxy-1-phenylbutyl)phenoxy)ethoxy)biphenyl-4-carboxylic acid::CHEMBL1271439

SMILES: CN(C)CCCC(O)(c1ccccc1)c1ccc(OCCOc2ccc(cc2)-c2ccc(cc2)C(O)=O)cc1

InChI Key: InChIKey=NYJJMCPHLCWNLP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329385   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))
BDBM50329385
PNG
(4'-(2-(4-(4-(dimethylamino)-1-hydroxy-1-phenylbuty...)
Show SMILES CN(C)CCCC(O)(c1ccccc1)c1ccc(OCCOc2ccc(cc2)-c2ccc(cc2)C(O)=O)cc1
Show InChI InChI=1S/C33H35NO5/c1-34(2)22-6-21-33(37,28-7-4-3-5-8-28)29-15-19-31(20-16-29)39-24-23-38-30-17-13-26(14-18-30)25-9-11-27(12-10-25)32(35)36/h3-5,7-20,37H,6,21-24H2,1-2H3,(H,35,36)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Bcl-2 by fluorescence polarization assay


Bioorg Med Chem Lett 20: 6587-91 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.033
BindingDB Entry DOI: 10.7270/Q2J103C3
More data for this
Ligand-Target Pair