BDBM50329581 (-)-9-Methylcytisine::CHEMBL1269418

SMILES: Cc1ccc2[C@H]3CNC[C@H](C3)Cn2c1=O

InChI Key: InChIKey=MYEABNSFVNHLCV-VHSXEESVSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50329581 ((-)-9-Methylcytisine | CHEMBL1269418) Show SMILES Cc1ccc2[C@H]3CNC[C@H](C3)Cn2c1=O |r,TLB:3:4:10:6.8.7,THB:13:12:10:6.8.7| Show InChI InChI=1S/C12H16N2O/c1-8-2-3-11-10-4-9(5-13-6-10)7-14(11)12(8)15/h2-3,9-10,13H,4-7H2,1H3/t9-,10+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSICAEN-Université de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]cytisine from rat alpha4beta2 nAChR in rat brain cell membrane				Bioorg Med Chem Lett 20: 6667-70 (2010) Article DOI: 10.1016/j.bmcl.2010.09.017 BindingDB Entry DOI: 10.7270/Q27M085J
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50329581 ((-)-9-Methylcytisine | CHEMBL1269418) Show SMILES Cc1ccc2[C@H]3CNC[C@H](C3)Cn2c1=O |r,TLB:3:4:10:6.8.7,THB:13:12:10:6.8.7| Show InChI InChI=1S/C12H16N2O/c1-8-2-3-11-10-4-9(5-13-6-10)7-14(11)12(8)15/h2-3,9-10,13H,4-7H2,1H3/t9-,10+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSICAEN-Université de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [125I]alphaBungarotoxin from alpha7 nAchR in rat brain cell membrane				Bioorg Med Chem Lett 20: 6667-70 (2010) Article DOI: 10.1016/j.bmcl.2010.09.017 BindingDB Entry DOI: 10.7270/Q27M085J
					More data for this Ligand-Target Pair