BDBM50329899 CHEMBL1271924::N-(6-(4-(allyloxy)-5-ethyl-6-methylpyrimidin-2-yl)pyridin-3-yl)-2-chloroacetamide

SMILES: CCc1c(C)nc(nc1OCC=C)-c1ccc(NC(=O)CCl)cn1

InChI Key: InChIKey=SDXKNGKMFQTFNM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329899 (CHEMBL1271924 | N-(6-(4-(allyloxy)-5-ethyl-6-methy...) Show SMILES CCc1c(C)nc(nc1OCC=C)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C17H19ClN4O2/c1-4-8-24-17-13(5-2)11(3)20-16(22-17)14-7-6-12(10-19-14)21-15(23)9-18/h4,6-7,10H,1,5,8-9H2,2-3H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329899 (CHEMBL1271924 | N-(6-(4-(allyloxy)-5-ethyl-6-methy...) Show SMILES CCc1c(C)nc(nc1OCC=C)-c1ccc(NC(=O)CCl)cn1 Show InChI InChI=1S/C17H19ClN4O2/c1-4-8-24-17-13(5-2)11(3)20-16(22-17)14-7-6-12(10-19-14)21-15(23)9-18/h4,6-7,10H,1,5,8-9H2,2-3H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under normoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair