BDBM50329901 2-(5-aminopyridin-2-yl)-5-chloro-6-methylpyrimidin-4-ol::CHEMBL1269394

SMILES: Cc1nc([nH]c(=O)c1Cl)-c1ccc(N)cn1

InChI Key: InChIKey=KOWIVPQBUIHTSO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50329901 (2-(5-aminopyridin-2-yl)-5-chloro-6-methylpyrimidin...) Show SMILES Cc1nc([nH]c(=O)c1Cl)-c1ccc(N)cn1 Show InChI InChI=1S/C10H9ClN4O/c1-5-8(11)10(16)15-9(14-5)7-3-2-6(12)4-13-7/h2-4H,12H2,1H3,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of HIF1alpha in human U251 cells under hypoxic condition by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 6426-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.083 BindingDB Entry DOI: 10.7270/Q2HX1CXM
					More data for this Ligand-Target Pair