BDBM50331393 4-(1-(2,3-dimethoxybenzyl)-1H-1,2,3-triazol-4-yl)phenol::CHEMBL1289631

SMILES: COc1cccc(Cn2cc(nn2)-c2ccc(O)cc2)c1OC

InChI Key: InChIKey=IAZNDXVEAROTIW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human))	BDBM50331393 (4-(1-(2,3-dimethoxybenzyl)-1H-1,2,3-triazol-4-yl)p...) Show SMILES COc1cccc(Cn2cc(nn2)-c2ccc(O)cc2)c1OC Show InChI InChI=1S/C17H17N3O3/c1-22-16-5-3-4-13(17(16)23-2)10-20-11-15(18-19-20)12-6-8-14(21)9-7-12/h3-9,11,21H,10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of human MIF tautomerase activity using 4-hydroxyphenylpyruvate as substrate				Bioorg Med Chem Lett 20: 7033-6 (2010) Article DOI: 10.1016/j.bmcl.2010.09.118 BindingDB Entry DOI: 10.7270/Q2RX9CB6
					More data for this Ligand-Target Pair