BDBM50331436 1-Methyl-1H-imidazole-4-carboxylic acid{3-[(1,1-dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-phenyl-amino]-propyl}-amide::CHEMBL1290061

SMILES: Cn1cnc(c1)C(=O)NCCCN(C1=NS(=O)(=O)c2ccccc12)c1ccccc1

InChI Key: InChIKey=OHRBGTHVWHYQAM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50331436 (1-Methyl-1H-imidazole-4-carboxylic acid{3-[(1,1-di...) Show SMILES Cn1cnc(c1)C(=O)NCCCN(C1=NS(=O)(=O)c2ccccc12)c1ccccc1 |t:14| Show InChI InChI=1S/C21H21N5O3S/c1-25-14-18(23-15-25)21(27)22-12-7-13-26(16-8-3-2-4-9-16)20-17-10-5-6-11-19(17)30(28,29)24-20/h2-6,8-11,14-15H,7,12-13H2,1H3,(H,22,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of human voltage-gated potassium channel Kv1.3 expressed in CGE22 cells by patch clamp assay				Bioorg Med Chem Lett 20: 6983-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.132 BindingDB Entry DOI: 10.7270/Q2N58MMS
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