BDBM50331471 3,3,3-Trifluoro-N-{3-[(6-fluoro-1,1-dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-phenyl-amino]-2,2-dimethyl-propyl}-2-hydroxy-2-methyl-propionamide::CHEMBL1289419

SMILES: CC(C)(CNC(=O)C(C)(O)C(F)(F)F)CN(C1=NS(=O)(=O)c2cc(F)ccc12)c1ccccc1

InChI Key: InChIKey=GAKQXDXJHZRVJC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50331471 (3,3,3-Trifluoro-N-{3-[(6-fluoro-1,1-dioxo-1H-1lamb...) Show SMILES CC(C)(CNC(=O)C(C)(O)C(F)(F)F)CN(C1=NS(=O)(=O)c2cc(F)ccc12)c1ccccc1 |t:16| Show InChI InChI=1S/C22H23F4N3O4S/c1-20(2,12-27-19(30)21(3,31)22(24,25)26)13-29(15-7-5-4-6-8-15)18-16-10-9-14(23)11-17(16)34(32,33)28-18/h4-11,31H,12-13H2,1-3H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 ion channel expressed in CHO K1 cells				Bioorg Med Chem Lett 20: 6989-92 (2010) Article DOI: 10.1016/j.bmcl.2010.09.131 BindingDB Entry DOI: 10.7270/Q2HD7VW2
					More data for this Ligand-Target Pair
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50331471 (3,3,3-Trifluoro-N-{3-[(6-fluoro-1,1-dioxo-1H-1lamb...) Show SMILES CC(C)(CNC(=O)C(C)(O)C(F)(F)F)CN(C1=NS(=O)(=O)c2cc(F)ccc12)c1ccccc1 |t:16| Show InChI InChI=1S/C22H23F4N3O4S/c1-20(2,12-27-19(30)21(3,31)22(24,25)26)13-29(15-7-5-4-6-8-15)18-16-10-9-14(23)11-17(16)34(32,33)28-18/h4-11,31H,12-13H2,1-3H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.3 ion channel expressed in CGE22 cells				Bioorg Med Chem Lett 20: 6989-92 (2010) Article DOI: 10.1016/j.bmcl.2010.09.131 BindingDB Entry DOI: 10.7270/Q2HD7VW2
					More data for this Ligand-Target Pair