BDBM50332236 (R)-6-(3-amino-3-methylpiperidin-1-yl)-5-benzyl-3-methyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione hydrochloride::CHEMBL1288231

SMILES: Cn1c(=O)[nH]c2cc(N3CCC[C@@](C)(N)C3)n(Cc3ccccc3)c2c1=O

InChI Key: InChIKey=AJXPXEUUDNOLBU-HXUWFJFHSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50332236 ((R)-6-(3-amino-3-methylpiperidin-1-yl)-5-benzyl-3-...) Show SMILES Cn1c(=O)[nH]c2cc(N3CCC[C@@](C)(N)C3)n(Cc3ccccc3)c2c1=O |r| Show InChI InChI=1S/C20H25N5O2/c1-20(21)9-6-10-24(13-20)16-11-15-17(18(26)23(2)19(27)22-15)25(16)12-14-7-4-3-5-8-14/h3-5,7-8,11H,6,9-10,12-13,21H2,1-2H3,(H,22,27)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human plasma DPP4				Bioorg Med Chem Lett 20: 7246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.101 BindingDB Entry DOI: 10.7270/Q2BK1CMK
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50332236 ((R)-6-(3-amino-3-methylpiperidin-1-yl)-5-benzyl-3-...) Show SMILES Cn1c(=O)[nH]c2cc(N3CCC[C@@](C)(N)C3)n(Cc3ccccc3)c2c1=O |r| Show InChI InChI=1S/C20H25N5O2/c1-20(21)9-6-10-24(13-20)16-11-15-17(18(26)23(2)19(27)22-15)25(16)12-14-7-4-3-5-8-14/h3-5,7-8,11H,6,9-10,12-13,21H2,1-2H3,(H,22,27)/t20-/m1/s1	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP9				Bioorg Med Chem Lett 20: 7246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.101 BindingDB Entry DOI: 10.7270/Q2BK1CMK
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50332236 ((R)-6-(3-amino-3-methylpiperidin-1-yl)-5-benzyl-3-...) Show SMILES Cn1c(=O)[nH]c2cc(N3CCC[C@@](C)(N)C3)n(Cc3ccccc3)c2c1=O |r| Show InChI InChI=1S/C20H25N5O2/c1-20(21)9-6-10-24(13-20)16-11-15-17(18(26)23(2)19(27)22-15)25(16)12-14-7-4-3-5-8-14/h3-5,7-8,11H,6,9-10,12-13,21H2,1-2H3,(H,22,27)/t20-/m1/s1	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP8				Bioorg Med Chem Lett 20: 7246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.101 BindingDB Entry DOI: 10.7270/Q2BK1CMK
					More data for this Ligand-Target Pair