BDBM50332237 (R)-2-((6-(3-amino-3-methylpiperidin-1-yl)-1,3-dimethyl-2,4-dioxo-3,4-dihydro-1H-pyrrolo[3,2-d]pyrimidin-5(2H)-yl)methyl)benzonitrile hydrochloride::CHEMBL1288232

SMILES: Cn1c2cc(N3CCC[C@@](C)(N)C3)n(Cc3ccccc3C#N)c2c(=O)n(C)c1=O

InChI Key: InChIKey=WHJPUFYUBTUSAK-JOCHJYFZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50332237 ((R)-2-((6-(3-amino-3-methylpiperidin-1-yl)-1,3-dim...) Show SMILES Cn1c2cc(N3CCC[C@@](C)(N)C3)n(Cc3ccccc3C#N)c2c(=O)n(C)c1=O |r| Show InChI InChI=1S/C22H26N6O2/c1-22(24)9-6-10-27(14-22)18-11-17-19(20(29)26(3)21(30)25(17)2)28(18)13-16-8-5-4-7-15(16)12-23/h4-5,7-8,11H,6,9-10,13-14,24H2,1-3H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human plasma DPP4				Bioorg Med Chem Lett 20: 7246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.101 BindingDB Entry DOI: 10.7270/Q2BK1CMK
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50332237 ((R)-2-((6-(3-amino-3-methylpiperidin-1-yl)-1,3-dim...) Show SMILES Cn1c2cc(N3CCC[C@@](C)(N)C3)n(Cc3ccccc3C#N)c2c(=O)n(C)c1=O |r| Show InChI InChI=1S/C22H26N6O2/c1-22(24)9-6-10-27(14-22)18-11-17-19(20(29)26(3)21(30)25(17)2)28(18)13-16-8-5-4-7-15(16)12-23/h4-5,7-8,11H,6,9-10,13-14,24H2,1-3H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP9				Bioorg Med Chem Lett 20: 7246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.101 BindingDB Entry DOI: 10.7270/Q2BK1CMK
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50332237 ((R)-2-((6-(3-amino-3-methylpiperidin-1-yl)-1,3-dim...) Show SMILES Cn1c2cc(N3CCC[C@@](C)(N)C3)n(Cc3ccccc3C#N)c2c(=O)n(C)c1=O |r| Show InChI InChI=1S/C22H26N6O2/c1-22(24)9-6-10-27(14-22)18-11-17-19(20(29)26(3)21(30)25(17)2)28(18)13-16-8-5-4-7-15(16)12-23/h4-5,7-8,11H,6,9-10,13-14,24H2,1-3H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP8				Bioorg Med Chem Lett 20: 7246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.101 BindingDB Entry DOI: 10.7270/Q2BK1CMK
					More data for this Ligand-Target Pair