BDBM50332378 4-Amino-7-fluoro-N-propyl-8-(pyrimidin-2-yl)cinnoline-3-carboxamide::CHEMBL1631470

SMILES: CCCNC(=O)c1nnc2c(c(F)ccc2c1N)-c1ncccn1

InChI Key: InChIKey=OKKCDBHXMZEFNG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50332378 (4-Amino-7-fluoro-N-propyl-8-(pyrimidin-2-yl)cinnol...) Show SMILES CCCNC(=O)c1nnc2c(c(F)ccc2c1N)-c1ncccn1 Show InChI InChI=1S/C16H15FN6O/c1-2-6-21-16(24)14-12(18)9-4-5-10(17)11(13(9)22-23-14)15-19-7-3-8-20-15/h3-5,7-8H,2,6H2,1H3,(H2,18,22)(H,21,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human alpha2beta3gamma2 GABA receptor in Sf9 membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 8374-82 (2010) Article DOI: 10.1016/j.bmc.2010.09.058 BindingDB Entry DOI: 10.7270/Q2FB536X
					More data for this Ligand-Target Pair