null
SMILES: Cc1nc(sc1C[Se]c1ccc(OCC(O)=O)c(C)c1)-c1ccc(c(F)c1)C(F)(F)F
InChI Key: InChIKey=DSEBHTXGMSLWQS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50332466 (2-(4-((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assay | Bioorg Med Chem Lett 20: 7239-42 (2010) Article DOI: 10.1016/j.bmcl.2010.10.103 BindingDB Entry DOI: 10.7270/Q2SN0975 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50332466 (2-(4-((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-me...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Agonist activity at human PPAR-gamma expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assay | Bioorg Med Chem Lett 20: 7239-42 (2010) Article DOI: 10.1016/j.bmcl.2010.10.103 BindingDB Entry DOI: 10.7270/Q2SN0975 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50332466 (2-(4-((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assay | Bioorg Med Chem Lett 20: 7239-42 (2010) Article DOI: 10.1016/j.bmcl.2010.10.103 BindingDB Entry DOI: 10.7270/Q2SN0975 | |||||||||||
More data for this Ligand-Target Pair |