BDBM50333470 2-(3-1H-indazol-5-ylureido)-N-benzyl-5-tert-butylthiophene-3-carboxamide::CHEMBL1641804

SMILES: CC(C)(C)c1cc(C(=O)NCc2ccccc2)c(NC(=O)Nc2ccc3[nH]ncc3c2)s1

InChI Key: InChIKey=KFIPEHWOFAOAMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase (P70S6K) (Homo sapiens (Human))	BDBM50333470 (2-(3-1H-indazol-5-ylureido)-N-benzyl-5-tert-butylt...) Show SMILES CC(C)(C)c1cc(C(=O)NCc2ccccc2)c(NC(=O)Nc2ccc3[nH]ncc3c2)s1 Show InChI InChI=1S/C24H25N5O2S/c1-24(2,3)20-12-18(21(30)25-13-15-7-5-4-6-8-15)22(32-20)28-23(31)27-17-9-10-19-16(11-17)14-26-29-19/h4-12,14H,13H2,1-3H3,(H,25,30)(H,26,29)(H2,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of S6K1				Bioorg Med Chem Lett 21: 849-52 (2011) Article DOI: 10.1016/j.bmcl.2010.11.069 BindingDB Entry DOI: 10.7270/Q289163D
					More data for this Ligand-Target Pair