BDBM50333518 5-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)isophthalonitrile::CHEMBL1641835

SMILES: N#Cc1cc(cc(c1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1)C#N

InChI Key: InChIKey=PXSUTFZDDIPUEP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50333518 (5-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-y...) Show SMILES N#Cc1cc(cc(c1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1)C#N Show InChI InChI=1S/C20H22N6S/c21-13-15-10-16(14-22)12-17(11-15)19-23-24-20(27-19)26-8-4-18(5-9-26)25-6-2-1-3-7-25/h10-12,18H,1-9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK cells after 30 mins by scintillation count...				Bioorg Med Chem Lett 21: 861-4 (2011) Article DOI: 10.1016/j.bmcl.2010.11.065 BindingDB Entry DOI: 10.7270/Q20V8D24
					More data for this Ligand-Target Pair