BDBM50334189 4-Cyano-N-(pyridin-3-yl)benzamide::CHEMBL1645412

SMILES: O=C(Nc1cccnc1)c1ccc(cc1)C#N

InChI Key: InChIKey=OMHXOAPLNZOELY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50334189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50334189 (4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412) Show SMILES O=C(Nc1cccnc1)c1ccc(cc1)C#N Show InChI InChI=1S/C13H9N3O/c14-8-10-3-5-11(6-4-10)13(17)16-12-2-1-7-15-9-12/h1-7,9H,(H,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University& Helmholtz Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrate				Bioorg Med Chem Lett 21: 186-90 (2010) Article DOI: 10.1016/j.bmcl.2010.11.040 BindingDB Entry DOI: 10.7270/Q2TX3FND
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (Homo sapiens (Human))	BDBM50334189 (4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412) Show SMILES O=C(Nc1cccnc1)c1ccc(cc1)C#N Show InChI InChI=1S/C13H9N3O/c14-8-10-3-5-11(6-4-10)13(17)16-12-2-1-7-15-9-12/h1-7,9H,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	454	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020)
					More data for this Ligand-Target Pair
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM50334189 (4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412) Show SMILES O=C(Nc1cccnc1)c1ccc(cc1)C#N Show InChI InChI=1S/C13H9N3O/c14-8-10-3-5-11(6-4-10)13(17)16-12-2-1-7-15-9-12/h1-7,9H,(H,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycortisol as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020)
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM50334189 (4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412) Show SMILES O=C(Nc1cccnc1)c1ccc(cc1)C#N Show InChI InChI=1S/C13H9N3O/c14-8-10-3-5-11(6-4-10)13(17)16-12-2-1-7-15-9-12/h1-7,9H,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University& Helmholtz Institute for Pharmaceutical Research Saarland Curated by ChEMBL					Assay Description Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrate				Bioorg Med Chem Lett 21: 186-90 (2010) Article DOI: 10.1016/j.bmcl.2010.11.040 BindingDB Entry DOI: 10.7270/Q2TX3FND
					More data for this Ligand-Target Pair