BDBM50335753 2-[2-(3-(R)-Aminopiperidin-1-yl)-6-oxo-5-vinyl-6H-pyrimidin-1-ylmethyl]benzonitrile::CHEMBL1650426

SMILES: N[C@@H]1CCCN(C1)c1ncc(C=C)c(=O)n1Cc1ccccc1C#N

InChI Key: InChIKey=MDASXAFCDDZWDX-QGZVFWFLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50335753 (2-[2-(3-(R)-Aminopiperidin-1-yl)-6-oxo-5-vinyl-6H-...) Show SMILES N[C@@H]1CCCN(C1)c1ncc(C=C)c(=O)n1Cc1ccccc1C#N |r| Show InChI InChI=1S/C19H21N5O/c1-2-14-11-22-19(23-9-5-8-17(21)13-23)24(18(14)25)12-16-7-4-3-6-15(16)10-20/h2-4,6-7,11,17H,1,5,8-9,12-13,21H2/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda San Diego, Inc. Curated by ChEMBL					Assay Description Inhibition of human DPP8				J Med Chem 54: 510-24 (2011) Article DOI: 10.1021/jm101016w BindingDB Entry DOI: 10.7270/Q24X5828
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50335753 (2-[2-(3-(R)-Aminopiperidin-1-yl)-6-oxo-5-vinyl-6H-...) Show SMILES N[C@@H]1CCCN(C1)c1ncc(C=C)c(=O)n1Cc1ccccc1C#N |r| Show InChI InChI=1S/C19H21N5O/c1-2-14-11-22-19(23-9-5-8-17(21)13-23)24(18(14)25)12-16-7-4-3-6-15(16)10-20/h2-4,6-7,11,17H,1,5,8-9,12-13,21H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Takeda San Diego, Inc. Curated by ChEMBL					Assay Description Inhibition of human DPP4				J Med Chem 54: 510-24 (2011) Article DOI: 10.1021/jm101016w BindingDB Entry DOI: 10.7270/Q24X5828
					More data for this Ligand-Target Pair