BDBM50335955 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(5-methoxypyrimidin-2-yl)biphenyl-3-yl)acetic acid::CHEMBL1668899

SMILES: CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)-c1ncc(OC)cn1)C(=O)C1CC1

InChI Key: InChIKey=XBEGSMBAOUVMHZ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50335955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50335955 (2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...) Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)-c1ncc(OC)cn1)C(=O)C1CC1 Show InChI InChI=1S/C27H29N3O5/c1-4-30(27(33)18-6-7-18)16-20-13-19(26-28-14-21(34-2)15-29-26)8-9-22(20)23-11-17(12-25(31)32)5-10-24(23)35-3/h5,8-11,13-15,18H,4,6-7,12,16H2,1-3H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
USA. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting				Bioorg Med Chem Lett 21: 1036-40 (2011) Article DOI: 10.1016/j.bmcl.2010.12.016 BindingDB Entry DOI: 10.7270/Q27P8ZNT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50335955 (2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...) Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)-c1ncc(OC)cn1)C(=O)C1CC1 Show InChI InChI=1S/C27H29N3O5/c1-4-30(27(33)18-6-7-18)16-20-13-19(26-28-14-21(34-2)15-29-26)8-9-22(20)23-11-17(12-25(31)32)5-10-24(23)35-3/h5,8-11,13-15,18H,4,6-7,12,16H2,1-3H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
USA. Curated by ChEMBL					Assay Description Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change by flow cytometry				Bioorg Med Chem Lett 21: 1036-40 (2011) Article DOI: 10.1016/j.bmcl.2010.12.016 BindingDB Entry DOI: 10.7270/Q27P8ZNT
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50335955 (2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...) Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)-c1ncc(OC)cn1)C(=O)C1CC1 Show InChI InChI=1S/C27H29N3O5/c1-4-30(27(33)18-6-7-18)16-20-13-19(26-28-14-21(34-2)15-29-26)8-9-22(20)23-11-17(12-25(31)32)5-10-24(23)35-3/h5,8-11,13-15,18H,4,6-7,12,16H2,1-3H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
USA. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSA				Bioorg Med Chem Lett 21: 1036-40 (2011) Article DOI: 10.1016/j.bmcl.2010.12.016 BindingDB Entry DOI: 10.7270/Q27P8ZNT
					More data for this Ligand-Target Pair