BDBM50335977 1-(1-Acetyl-piperidin-4-yl)-3-(3-fluoro-adamantan-1-yl)-urea::CHEMBL1668923

SMILES: CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(F)(CC(F)(C3)C1)C2

InChI Key: InChIKey=LRLXBDNGOOHPQK-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335977 (1-(1-Acetyl-piperidin-4-yl)-3-(3-fluoro-adamantan-...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(F)(CC(F)(C3)C1)C2 |TLB:16:17:23:22.15.14,18:17:23:22.15.14,18:17:20.22.23:14,21:20:17.16.24:14,THB:16:15:19.17.24:23,19:20:17.16.24:14,19:17:20.22.23:14| Show InChI InChI=1S/C18H27F2N3O2/c1-12(24)23-4-2-14(3-5-23)21-15(25)22-18-8-13-6-16(19,10-18)9-17(20,7-13)11-18/h13-14H,2-11H2,1H3,(H2,21,22,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
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