BDBM50336451 1-(1H-Indol-2-yl)-2-pyridin-3-yl-propan-1-one::CHEMBL1668398

SMILES: CC(C(=O)c1cc2ccccc2[nH]1)c1cccnc1

InChI Key: InChIKey=OGSFROUGHQWSDV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50336451 (1-(1H-Indol-2-yl)-2-pyridin-3-yl-propan-1-one | CH...) Show SMILES CC(C(=O)c1cc2ccccc2[nH]1)c1cccnc1 Show InChI InChI=1S/C16H14N2O/c1-11(13-6-4-8-17-10-13)16(19)15-9-12-5-2-3-7-14(12)18-15/h2-11,18H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibition of human IDO activity by spectrophotometry				Bioorg Med Chem 19: 1550-61 (2011) Article DOI: 10.1016/j.bmc.2010.12.032 BindingDB Entry DOI: 10.7270/Q27M087F
					More data for this Ligand-Target Pair