BDBM50336795 CHEMBL1672099::Sodium 1-amino-4-(3,5-difluorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate

SMILES: Nc1c(cc(Nc2cc(F)cc(F)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O

InChI Key: InChIKey=RWTLBALVZXOAHG-UHFFFAOYSA-M

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyrimidinergic receptor P2Y4 (Homo sapiens (Human))	BDBM50336795 (CHEMBL1672099 | Sodium 1-amino-4-(3,5-difluorophen...) Show SMILES Nc1c(cc(Nc2cc(F)cc(F)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O Show InChI InChI=1S/C20H12F2N2O5S/c21-9-5-10(22)7-11(6-9)24-14-8-15(30(27,28)29)18(23)17-16(14)19(25)12-3-1-2-4-13(12)20(17)26/h1-8,24H,23H2,(H,27,28,29)/p-1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilizati...				J Med Chem 60: 3020-3038 (2017) Article DOI: 10.1021/acs.jmedchem.7b00030 BindingDB Entry DOI: 10.7270/Q2G73H15
					More data for this Ligand-Target Pair
Purinergic, P2X2 (RAT)	BDBM50336795 (CHEMBL1672099 | Sodium 1-amino-4-(3,5-difluorophen...) Show SMILES Nc1c(cc(Nc2cc(F)cc(F)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O Show InChI InChI=1S/C20H12F2N2O5S/c21-9-5-10(22)7-11(6-9)24-14-8-15(30(27,28)29)18(23)17-16(14)19(25)12-3-1-2-4-13(12)20(17)26/h1-8,24H,23H2,(H,27,28,29)/p-1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Antagonist activity against rat P2X2 receptor expressed in Xenopus laevis oocyte assessed as inhibition of alpha, beta-meATP-induced inward current b...				J Med Chem 54: 817-30 (2012) Article DOI: 10.1021/jm1012193 BindingDB Entry DOI: 10.7270/Q2VH5PTG
					More data for this Ligand-Target Pair