BDBM50336808 CHEMBL1672115::[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetic Acid Dihydrochloride

SMILES: CC(C)Cc1nc(C)c(CC(O)=O)c(-c2ccc(C)cc2)c1CN

InChI Key: InChIKey=CENHBINXUBIJGD-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50336808 (CHEMBL1672115 | [5-(Aminomethyl)-2-methyl-4-(4-met...) Show SMILES CC(C)Cc1nc(C)c(CC(O)=O)c(-c2ccc(C)cc2)c1CN Show InChI InChI=1S/C20H26N2O2/c1-12(2)9-18-17(11-21)20(15-7-5-13(3)6-8-15)16(10-19(23)24)14(4)22-18/h5-8,12H,9-11,21H2,1-4H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of DPP4 in human Caco2 cells after 60 mins				J Med Chem 54: 831-50 (2012) Article DOI: 10.1021/jm101236h BindingDB Entry DOI: 10.7270/Q2QR4Z4M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50336808 (CHEMBL1672115 | [5-(Aminomethyl)-2-methyl-4-(4-met...) Show SMILES CC(C)Cc1nc(C)c(CC(O)=O)c(-c2ccc(C)cc2)c1CN Show InChI InChI=1S/C20H26N2O2/c1-12(2)9-18-17(11-21)20(15-7-5-13(3)6-8-15)16(10-19(23)24)14(4)22-18/h5-8,12H,9-11,21H2,1-4H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of FLAG-tagged human DPP9 expressed in human 293F cells after 90 mins				J Med Chem 54: 831-50 (2012) Article DOI: 10.1021/jm101236h BindingDB Entry DOI: 10.7270/Q2QR4Z4M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50336808 (CHEMBL1672115 | [5-(Aminomethyl)-2-methyl-4-(4-met...) Show SMILES CC(C)Cc1nc(C)c(CC(O)=O)c(-c2ccc(C)cc2)c1CN Show InChI InChI=1S/C20H26N2O2/c1-12(2)9-18-17(11-21)20(15-7-5-13(3)6-8-15)16(10-19(23)24)14(4)22-18/h5-8,12H,9-11,21H2,1-4H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of FLAG-tagged human DPP8 expressed in human 293F cells after 90 mins				J Med Chem 54: 831-50 (2012) Article DOI: 10.1021/jm101236h BindingDB Entry DOI: 10.7270/Q2QR4Z4M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase II (Rattus norvegicus)	BDBM50336808 (CHEMBL1672115 | [5-(Aminomethyl)-2-methyl-4-(4-met...) Show SMILES CC(C)Cc1nc(C)c(CC(O)=O)c(-c2ccc(C)cc2)c1CN Show InChI InChI=1S/C20H26N2O2/c1-12(2)9-18-17(11-21)20(15-7-5-13(3)6-8-15)16(10-19(23)24)14(4)22-18/h5-8,12H,9-11,21H2,1-4H3,(H,23,24)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of rat kidney DPP2 after 60 mins				J Med Chem 54: 831-50 (2012) Article DOI: 10.1021/jm101236h BindingDB Entry DOI: 10.7270/Q2QR4Z4M
					More data for this Ligand-Target Pair