BDBM50336847 2-(4-((5-(2-chlorophenyl)-6-(ethoxycarbonyl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidin-2-ylidene)methyl)-2-methoxy-6-methylphenoxy)acetic acid::CHEMBL1672294

SMILES: CCOC(=O)C1=C(C)N=c2s\c(=C/c3cc(C)c(OCC(O)=O)c(OC)c3)c(=O)n2C1c1ccccc1Cl

InChI Key: InChIKey=CTJIZFFMITUMOP-NDENLUEZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50336847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM50336847 (2-(4-((5-(2-chlorophenyl)-6-(ethoxycarbonyl)-7-met...) Show SMILES CCOC(=O)C1=C(C)N=c2s\c(=C/c3cc(C)c(OCC(O)=O)c(OC)c3)c(=O)n2C1c1ccccc1Cl |c:5,t:8| Show InChI InChI=1S/C27H25ClN2O7S/c1-5-36-26(34)22-15(3)29-27-30(23(22)17-8-6-7-9-18(17)28)25(33)20(38-27)12-16-10-14(2)24(19(11-16)35-4)37-13-21(31)32/h6-12,23H,5,13H2,1-4H3,(H,31,32)/b20-12-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant HePTP expressed in Escherichia coli				ACS Med Chem Lett 2: 113-118 (2011) Article DOI: 10.1021/ml100103p BindingDB Entry DOI: 10.7270/Q2319WWQ
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Homo sapiens (Human))	BDBM50336847 (2-(4-((5-(2-chlorophenyl)-6-(ethoxycarbonyl)-7-met...) Show SMILES CCOC(=O)C1=C(C)N=c2s\c(=C/c3cc(C)c(OCC(O)=O)c(OC)c3)c(=O)n2C1c1ccccc1Cl |c:5,t:8| Show InChI InChI=1S/C27H25ClN2O7S/c1-5-36-26(34)22-15(3)29-27-30(23(22)17-8-6-7-9-18(17)28)25(33)20(38-27)12-16-10-14(2)24(19(11-16)35-4)37-13-21(31)32/h6-12,23H,5,13H2,1-4H3,(H,31,32)/b20-12-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant MKP3 expressed in Escherichia coli				ACS Med Chem Lett 2: 113-118 (2011) Article DOI: 10.1021/ml100103p BindingDB Entry DOI: 10.7270/Q2319WWQ
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM50336847 (2-(4-((5-(2-chlorophenyl)-6-(ethoxycarbonyl)-7-met...) Show SMILES CCOC(=O)C1=C(C)N=c2s\c(=C/c3cc(C)c(OCC(O)=O)c(OC)c3)c(=O)n2C1c1ccccc1Cl |c:5,t:8| Show InChI InChI=1S/C27H25ClN2O7S/c1-5-36-26(34)22-15(3)29-27-30(23(22)17-8-6-7-9-18(17)28)25(33)20(38-27)12-16-10-14(2)24(19(11-16)35-4)37-13-21(31)32/h6-12,23H,5,13H2,1-4H3,(H,31,32)/b20-12-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant VHR expressed in Escherichia coli				ACS Med Chem Lett 2: 113-118 (2011) Article DOI: 10.1021/ml100103p BindingDB Entry DOI: 10.7270/Q2319WWQ
					More data for this Ligand-Target Pair