BDBM50336857 11-hydroxy-N-(3-fluoropropyl)aporphine::CHEMBL1672302

SMILES: Oc1cccc2C[C@H]3N(CCCF)CCc4cccc(c34)-c12

InChI Key: InChIKey=VAURMGBDDSMOJD-MRXNPFEDSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50336857 (11-hydroxy-N-(3-fluoropropyl)aporphine | CHEMBL167...) Show SMILES Oc1cccc2C[C@H]3N(CCCF)CCc4cccc(c34)-c12 |r| Show InChI InChI=1S/C19H20FNO/c20-9-3-10-21-11-8-13-4-1-6-15-18(13)16(21)12-14-5-2-7-17(22)19(14)15/h1-2,4-7,16,22H,3,8-12H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]domperidone from dopamine D2 receptor high binding site in Sprague-Dawley rat striatum by scintillation counting				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50336857 (11-hydroxy-N-(3-fluoropropyl)aporphine | CHEMBL167...) Show SMILES Oc1cccc2C[C@H]3N(CCCF)CCc4cccc(c34)-c12 |r| Show InChI InChI=1S/C19H20FNO/c20-9-3-10-21-11-8-13-4-1-6-15-18(13)16(21)12-14-5-2-7-17(22)19(14)15/h1-2,4-7,16,22H,3,8-12H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D2 receptor low binding site in Sprague-Dawley rat striatum by scintillation counting				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50336857 (11-hydroxy-N-(3-fluoropropyl)aporphine | CHEMBL167...) Show SMILES Oc1cccc2C[C@H]3N(CCCF)CCc4cccc(c34)-c12 |r| Show InChI InChI=1S/C19H20FNO/c20-9-3-10-21-11-8-13-4-1-6-15-18(13)16(21)12-14-5-2-7-17(22)19(14)15/h1-2,4-7,16,22H,3,8-12H2/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor low binding site by radioligand displacement assay				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50336857 (11-hydroxy-N-(3-fluoropropyl)aporphine | CHEMBL167...) Show SMILES Oc1cccc2C[C@H]3N(CCCF)CCc4cccc(c34)-c12 |r| Show InChI InChI=1S/C19H20FNO/c20-9-3-10-21-11-8-13-4-1-6-15-18(13)16(21)12-14-5-2-7-17(22)19(14)15/h1-2,4-7,16,22H,3,8-12H2/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]domperidone from human cloned dopamine D3 receptor expressed in mouse CCL1-3 cells by scintillation counting				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
					More data for this Ligand-Target Pair