BDBM50337772 CHEMBL1683491::ethyl 6-((3-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)thiazolidine-2-carboxamido)methyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxylate hydrochloride

SMILES: CCOC(=O)C1COc2cc(CNC(=O)C3SCCN3C(=O)C[C@H](N)Cc3cc(F)c(F)cc3F)ccc2O1

InChI Key: InChIKey=SOOMSOFJGXDQPT-PKZZPTEUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50337772 (CHEMBL1683491 | ethyl 6-((3-((R)-3-amino-4-(2,4,5-...) Show SMILES CCOC(=O)C1COc2cc(CNC(=O)C3SCCN3C(=O)C[C@H](N)Cc3cc(F)c(F)cc3F)ccc2O1 |r| Show InChI InChI=1S/C26H28F3N3O6S/c1-2-36-26(35)22-13-37-21-7-14(3-4-20(21)38-22)12-31-24(34)25-32(5-6-39-25)23(33)10-16(30)8-15-9-18(28)19(29)11-17(15)27/h3-4,7,9,11,16,22,25H,2,5-6,8,10,12-13,30H2,1H3,(H,31,34)/t16-,22?,25?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate reader				Bioorg Med Chem Lett 21: 1366-70 (2011) Article DOI: 10.1016/j.bmcl.2011.01.041 BindingDB Entry DOI: 10.7270/Q25B02R9
					More data for this Ligand-Target Pair