BDBM50338506 1-((3S,4S)-4-amino-1-(6-(2,4,5-trifluorophenyl)pyrimidin-4-yl)pyrrolidin-3-yl)piperidin-2-one::CHEMBL1683559

SMILES: N[C@H]1CN(C[C@@H]1N1CCCCC1=O)c1cc(ncn1)-c1cc(F)c(F)cc1F

InChI Key: InChIKey=ZSJZHAJFTNGTOQ-RDJZCZTQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338506   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50338506 (1-((3S,4S)-4-amino-1-(6-(2,4,5-trifluorophenyl)pyr...) Show SMILES N[C@H]1CN(C[C@@H]1N1CCCCC1=O)c1cc(ncn1)-c1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H20F3N5O/c20-12-6-14(22)13(21)5-11(12)16-7-18(25-10-24-16)26-8-15(23)17(9-26)27-4-2-1-3-19(27)28/h5-7,10,15,17H,1-4,8-9,23H2/t15-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair