BDBM50338777 CHEMBL1684405::N-(cyclopropylmethyl)-2-(2-(4-fluorophenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)acetamide

SMILES: Fc1ccc(cc1)-c1nc2ccc(OCCCN3CCOCC3)cc2c(=O)n1CC(=O)NCC1CC1

InChI Key: InChIKey=OTZWFHDNRCNYJO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1b receptor (Homo sapiens (Human))	BDBM50338777 (CHEMBL1684405 | N-(cyclopropylmethyl)-2-(2-(4-fluo...) Show SMILES Fc1ccc(cc1)-c1nc2ccc(OCCCN3CCOCC3)cc2c(=O)n1CC(=O)NCC1CC1 Show InChI InChI=1S/C27H31FN4O4/c28-21-6-4-20(5-7-21)26-30-24-9-8-22(36-13-1-10-31-11-14-35-15-12-31)16-23(24)27(34)32(26)18-25(33)29-17-19-2-3-19/h4-9,16,19H,1-3,10-15,17-18H2,(H,29,33)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Displacement of [3H]AVP from human V1b receptor expressed in CHO cells co-expressing VIP-luciferase by whole cell binding assay				Bioorg Med Chem Lett 21: 1871-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.081 BindingDB Entry DOI: 10.7270/Q2BR8SG4
					More data for this Ligand-Target Pair