BDBM50338814 (R)-N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)-4-(4-(4-(trifluoromethyl)phenyl)thiazol-2-yl)benzenesulfonamide::CHEMBL1684578

SMILES: O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2nc(cs2)-c2ccc(cc2)C(F)(F)F)cc1)c1ccccc1

InChI Key: InChIKey=SIAQPNFTQQNHGO-PMERELPUSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50338814 ((R)-N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)ph...) Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2nc(cs2)-c2ccc(cc2)C(F)(F)F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C32H28F3N3O3S2/c33-32(34,35)26-12-8-23(9-13-26)29-21-42-31(37-29)25-10-16-28(17-11-25)43(40,41)38-27-14-6-22(7-15-27)18-19-36-20-30(39)24-4-2-1-3-5-24/h1-17,21,30,36,38-39H,18-20H2/t30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta2 adrenergic receptor				Bioorg Med Chem Lett 21: 1865-70 (2011) Article DOI: 10.1016/j.bmcl.2010.12.087 BindingDB Entry DOI: 10.7270/Q27081R3
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50338814 ((R)-N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)ph...) Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2nc(cs2)-c2ccc(cc2)C(F)(F)F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C32H28F3N3O3S2/c33-32(34,35)26-12-8-23(9-13-26)29-21-42-31(37-29)25-10-16-28(17-11-25)43(40,41)38-27-14-6-22(7-15-27)18-19-36-20-30(39)24-4-2-1-3-5-24/h1-17,21,30,36,38-39H,18-20H2/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta1 adrenergic receptor				Bioorg Med Chem Lett 21: 1865-70 (2011) Article DOI: 10.1016/j.bmcl.2010.12.087 BindingDB Entry DOI: 10.7270/Q27081R3
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50338814 ((R)-N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)ph...) Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2nc(cs2)-c2ccc(cc2)C(F)(F)F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C32H28F3N3O3S2/c33-32(34,35)26-12-8-23(9-13-26)29-21-42-31(37-29)25-10-16-28(17-11-25)43(40,41)38-27-14-6-22(7-15-27)18-19-36-20-30(39)24-4-2-1-3-5-24/h1-17,21,30,36,38-39H,18-20H2/t30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta3 adrenergic receptor				Bioorg Med Chem Lett 21: 1865-70 (2011) Article DOI: 10.1016/j.bmcl.2010.12.087 BindingDB Entry DOI: 10.7270/Q27081R3
					More data for this Ligand-Target Pair