BDBM50338822 1-(4,5-dihydro-3-(naphth-1-yl)-5-(4-nitrophenyl)-1H-pyrazol-1-yl)ethanone::CHEMBL1684752

SMILES: CC(=O)N1N=C(CC1c1ccc(cc1)[N+]([O-])=O)c1cccc2ccccc12

InChI Key: InChIKey=NRHWHYDIWIYRPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase (Bos taurus (Bovine))	BDBM50338822 (1-(4,5-dihydro-3-(naphth-1-yl)-5-(4-nitrophenyl)-1...) Show SMILES CC(=O)N1N=C(CC1c1ccc(cc1)[N+]([O-])=O)c1cccc2ccccc12 |c:4| Show InChI InChI=1S/C21H17N3O3/c1-14(25)23-21(16-9-11-17(12-10-16)24(26)27)13-20(22-23)19-8-4-6-15-5-2-3-7-18(15)19/h2-12,21H,13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indo-Soviet Friendship College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of bovine Xanthine oxidase assessed as decrease in uric acid production preincubated at 293 nM of compound for 5 mins by spectrophotometry				Bioorg Med Chem 19: 1950-8 (2011) Article DOI: 10.1016/j.bmc.2011.01.058 BindingDB Entry DOI: 10.7270/Q237791S
					More data for this Ligand-Target Pair