BDBM50338824 1-(4,5-Dihydro-5-(4-methoxyphenyl)-3-(naphth-1-yl)-1H-pyrazol-1-yl)ethanone::CHEMBL1684754

SMILES: COc1ccc(cc1)C1CC(=NN1C(C)=O)c1cccc2ccccc12

InChI Key: InChIKey=YUTPRLHWKSXVGY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase (Bos taurus (Bovine))	BDBM50338824 (1-(4,5-Dihydro-5-(4-methoxyphenyl)-3-(naphth-1-yl)...) Show SMILES COc1ccc(cc1)C1CC(=NN1C(C)=O)c1cccc2ccccc12 |c:11| Show InChI InChI=1S/C22H20N2O2/c1-15(25)24-22(17-10-12-18(26-2)13-11-17)14-21(23-24)20-9-5-7-16-6-3-4-8-19(16)20/h3-13,22H,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indo-Soviet Friendship College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of bovine Xanthine oxidase assessed as decrease in uric acid production preincubated at 293 nM of compound for 5 mins by spectrophotometry				Bioorg Med Chem 19: 1950-8 (2011) Article DOI: 10.1016/j.bmc.2011.01.058 BindingDB Entry DOI: 10.7270/Q237791S
					More data for this Ligand-Target Pair