BDBM50338833 1-(5-(Benzo[d][1,3]dioxol-5-yl)-4,5-dihydro-3-(naphth-1-yl)-1H-pyrazol-1-yl)ethanone::CHEMBL1684763
SMILES: CC(=O)N1N=C(CC1c1ccc2OCOc2c1)c1cccc2ccccc12
InChI Key: InChIKey=QFOXTVJYKRBAOM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Xanthine dehydrogenase (Bos taurus (Bovine)) | BDBM50338833 (1-(5-(Benzo[d][1,3]dioxol-5-yl)-4,5-dihydro-3-(nap...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indo-Soviet Friendship College of Pharmacy Curated by ChEMBL | Assay Description Inhibition of bovine Xanthine oxidase assessed as decrease in uric acid production preincubated at 293 nM of compound for 5 mins by spectrophotometry | Bioorg Med Chem 19: 1950-8 (2011) Article DOI: 10.1016/j.bmc.2011.01.058 BindingDB Entry DOI: 10.7270/Q237791S | |||||||||||
More data for this Ligand-Target Pair |