BDBM50338858 1-Acetyl-5-(4-hydroxy-3-methoxy)-3-phenyl-4,5-dihydro-((1H)pyrazole::CHEMBL1684637
SMILES: COc1cc(ccc1O)C1CC(=NN1C(C)=O)c1ccccc1
InChI Key: InChIKey=LBHCBNVUCHSTNV-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Xanthine dehydrogenase (Bos taurus (Bovine)) | BDBM50338858![]() (1-Acetyl-5-(4-hydroxy-3-methoxy)-3-phenyl-4,5-dihy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indo-Soviet Friendship College of Pharmacy Curated by ChEMBL | Assay Description Inhibition of bovine Xanthine oxidase assessed as decrease in uric acid production preincubated at 293 nM of compound for 5 mins by spectrophotometry | Bioorg Med Chem 19: 1950-8 (2011) Article DOI: 10.1016/j.bmc.2011.01.058 BindingDB Entry DOI: 10.7270/Q237791S | |||||||||||
More data for this Ligand-Target Pair |