BDBM50339025 6-(6-Amino-2-pyridinyl)-1H-indazol-3-amine::CHEMBL1688218

SMILES: Nc1n[nH]c2cc(ccc12)-c1cccc(N)n1

InChI Key: InChIKey=RAQJQSOFLNFNRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide dependent protein kinase-1 (Homo sapiens (Human))	BDBM50339025 (6-(6-Amino-2-pyridinyl)-1H-indazol-3-amine | CHEMB...) Show SMILES Nc1n[nH]c2cc(ccc12)-c1cccc(N)n1 Show InChI InChI=1S/C12H11N5/c13-11-3-1-2-9(15-11)7-4-5-8-10(6-7)16-17-12(8)14/h1-6H,(H2,13,15)(H3,14,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...				ACS Med Chem Lett 1: 439-442 (2010) Article DOI: 10.1021/ml100136n BindingDB Entry DOI: 10.7270/Q22807WJ
					More data for this Ligand-Target Pair