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SMILES: Cc1nc(cc(-c2ccc(F)cc2)c1CN)C(=O)N1CCCC1

InChI Key: InChIKey=HRXLRMFHWWQGLS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50339096 ((5-(aminomethyl)-4-(4-fluorophenyl)-6-methylpyridi...) Show SMILES Cc1nc(cc(-c2ccc(F)cc2)c1CN)C(=O)N1CCCC1 Show InChI InChI=1S/C18H20FN3O/c1-12-16(11-20)15(13-4-6-14(19)7-5-13)10-17(21-12)18(23)22-8-2-3-9-22/h4-7,10H,2-3,8-9,11,20H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.37E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...				ACS Med Chem Lett 1: 530-535 (2010) Article DOI: 10.1021/ml100200c BindingDB Entry DOI: 10.7270/Q2513ZGH
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50339096 ((5-(aminomethyl)-4-(4-fluorophenyl)-6-methylpyridi...) Show SMILES Cc1nc(cc(-c2ccc(F)cc2)c1CN)C(=O)N1CCCC1 Show InChI InChI=1S/C18H20FN3O/c1-12-16(11-20)15(13-4-6-14(19)7-5-13)10-17(21-12)18(23)22-8-2-3-9-22/h4-7,10H,2-3,8-9,11,20H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	686	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...				ACS Med Chem Lett 1: 530-535 (2010) Article DOI: 10.1021/ml100200c BindingDB Entry DOI: 10.7270/Q2513ZGH
					More data for this Ligand-Target Pair