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SMILES: Cc1cc(NC(=O)c2cc(c(CN)c(C)n2)-c2ccc(F)cc2F)no1

InChI Key: InChIKey=QKUNDPMYLQLBAM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50339099 (5-(aminomethyl)-4-(2,4-difluorophenyl)-6-methyl-N-...) Show SMILES Cc1cc(NC(=O)c2cc(c(CN)c(C)n2)-c2ccc(F)cc2F)no1 Show InChI InChI=1S/C18H16F2N4O2/c1-9-5-17(24-26-9)23-18(25)16-7-13(14(8-21)10(2)22-16)12-4-3-11(19)6-15(12)20/h3-7H,8,21H2,1-2H3,(H,23,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.79E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...				ACS Med Chem Lett 1: 530-535 (2010) Article DOI: 10.1021/ml100200c BindingDB Entry DOI: 10.7270/Q2513ZGH
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50339099 (5-(aminomethyl)-4-(2,4-difluorophenyl)-6-methyl-N-...) Show SMILES Cc1cc(NC(=O)c2cc(c(CN)c(C)n2)-c2ccc(F)cc2F)no1 Show InChI InChI=1S/C18H16F2N4O2/c1-9-5-17(24-26-9)23-18(25)16-7-13(14(8-21)10(2)22-16)12-4-3-11(19)6-15(12)20/h3-7H,8,21H2,1-2H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	674	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...				ACS Med Chem Lett 1: 530-535 (2010) Article DOI: 10.1021/ml100200c BindingDB Entry DOI: 10.7270/Q2513ZGH
					More data for this Ligand-Target Pair