BDBM50339103 5-Aminomethyl-4-(2,4-dichlorophenyl)-6-methyl-pyridine-2-carboxylic acid cyanomethyl-amide::CHEMBL1688431

SMILES: Cc1nc(cc(c1CN)-c1ccc(Cl)cc1Cl)C(=O)NCC#N

InChI Key: InChIKey=GWFVXNYRMACYQP-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50339103 (5-Aminomethyl-4-(2,4-dichlorophenyl)-6-methyl-pyri...) Show SMILES Cc1nc(cc(c1CN)-c1ccc(Cl)cc1Cl)C(=O)NCC#N Show InChI InChI=1S/C16H14Cl2N4O/c1-9-13(8-20)12(11-3-2-10(17)6-14(11)18)7-15(22-9)16(23)21-5-4-19/h2-3,6-7H,5,8,20H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP8 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...				ACS Med Chem Lett 1: 530-535 (2010) Article DOI: 10.1021/ml100200c BindingDB Entry DOI: 10.7270/Q2513ZGH
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50339103 (5-Aminomethyl-4-(2,4-dichlorophenyl)-6-methyl-pyri...) Show SMILES Cc1nc(cc(c1CN)-c1ccc(Cl)cc1Cl)C(=O)NCC#N Show InChI InChI=1S/C16H14Cl2N4O/c1-9-13(8-20)12(11-3-2-10(17)6-14(11)18)7-15(22-9)16(23)21-5-4-19/h2-3,6-7H,5,8,20H2,1H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...				ACS Med Chem Lett 1: 530-535 (2010) Article DOI: 10.1021/ml100200c BindingDB Entry DOI: 10.7270/Q2513ZGH
					More data for this Ligand-Target Pair