BDBM50339110 (5-(aminomethyl)-4-(4-methoxyphenyl)-6-methylpyridin-2-yl)(4-aminopiperidin-1-yl)methanone::CHEMBL1688438

SMILES: COc1ccc(cc1)-c1cc(nc(C)c1CN)C(=O)N1CCC(N)CC1

InChI Key: InChIKey=MLETZXUZFPFJJP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50339110 ((5-(aminomethyl)-4-(4-methoxyphenyl)-6-methylpyrid...) Show SMILES COc1ccc(cc1)-c1cc(nc(C)c1CN)C(=O)N1CCC(N)CC1 Show InChI InChI=1S/C20H26N4O2/c1-13-18(12-21)17(14-3-5-16(26-2)6-4-14)11-19(23-13)20(25)24-9-7-15(22)8-10-24/h3-6,11,15H,7-10,12,21-22H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...				ACS Med Chem Lett 1: 530-535 (2010) Article DOI: 10.1021/ml100200c BindingDB Entry DOI: 10.7270/Q2513ZGH
					More data for this Ligand-Target Pair