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SMILES: COc1ccc(cc1)-c1cc(nc(C)c1CN)C(=O)NCCN1CCNCC1

InChI Key: InChIKey=BXLOULNMWMTLHP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339111   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50339111
PNG
(5-(aminomethyl)-4-(4-methoxyphenyl)-6-methyl-N-(2-...)
Show SMILES COc1ccc(cc1)-c1cc(nc(C)c1CN)C(=O)NCCN1CCNCC1
Show InChI InChI=1S/C21H29N5O2/c1-15-19(14-22)18(16-3-5-17(28-2)6-4-16)13-20(25-15)21(27)24-9-12-26-10-7-23-8-11-26/h3-6,13,23H,7-12,14,22H2,1-2H3,(H,24,27)
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n/an/a>5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...

ACS Med Chem Lett 1: 530-535 (2010)


Article DOI: 10.1021/ml100200c
BindingDB Entry DOI: 10.7270/Q2513ZGH
More data for this
Ligand-Target Pair