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SMILES: Cc1nc(CN)cc(-c2ccccc2F)c1C(N)=O

InChI Key: InChIKey=IHGBQUVYSQVELH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339112   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50339112
PNG
(6-(aminomethyl)-4-(2-fluorophenyl)-2-methylnicotin...)
Show SMILES Cc1nc(CN)cc(-c2ccccc2F)c1C(N)=O
Show InChI InChI=1S/C14H14FN3O/c1-8-13(14(17)19)11(6-9(7-16)18-8)10-4-2-3-5-12(10)15/h2-6H,7,16H2,1H3,(H2,17,19)
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n/an/a>5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA chromogrnic substrate cleavage for 16 mins preincubated with compound for 10 mins before...

ACS Med Chem Lett 1: 530-535 (2010)


Article DOI: 10.1021/ml100200c
BindingDB Entry DOI: 10.7270/Q2513ZGH
More data for this
Ligand-Target Pair